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The lowest effective dose of an antidepressant for managing fibromyalgia symptoms typically involves options like amitriptyline or duloxetine. Amitriptyline is often prescribed at doses starting around 10-25 mg per day, while duloxetine may start at 30 mg per day. These medications can help alleviate pain and improve sleep in fibromyalgia patients, but it's essential for individuals to consult with a healthcare provider to determine the most appropriate dosage for their specific needs.

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1mo ago

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There are two antidepressants commonly used to treat Fibromyalgia, they are Savalla and Cymbalta. Both Savella and Cymbalta are serotonin and norepinephrine reuptake inhibitors (SNRI), similar to many other antidepressants; however, it is not considered an antidepressant, and is approved for the treatment of Fibromyalgia. Cymbalta, however, is used to treat not only Fibromyalgia but also depression, anxiety, and diabetic peripheral neuropathy. A doctor may prescribe either of these for Fibromyalgia. As with any medication, different people react differently so one may work better for a particular person than another. It is important to understand that doctors do not prescribe these medications to Fibromyalgia patients to treat depression, but rather because they have been proven to decrease the joint and muscle pains associated with Fibromyalgia.


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