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Cancer cells and normal cells in lung tissue differ in several key aspects, primarily due to genetic mutations and alterations in cellular behavior that drive the development and progression of cancer. Here are some of the fundamental differences between cancer cells and normal lung cells:

Uncontrolled Growth and Division:

Cancer Cells: Cancer cells have lost the normal regulatory mechanisms that control cell growth and division. They divide and replicate at an abnormally rapid rate, leading to the formation of tumors.

Normal Cells: Normal lung cells follow a controlled and regulated process of growth and division, ensuring that new cells are produced only when needed.

Genetic Mutations:

Cancer Cells: Cancer cells often harbor genetic mutations or alterations in their DNA. These mutations can activate oncogenes (genes that promote cell growth) and inhibit tumor suppressor genes (genes that regulate cell division and prevent tumor formation).

Normal Cells: Normal lung cells have intact and functional DNA that maintains the proper balance between cell growth and cell death.

Loss of Apoptosis:

Cancer Cells: Cancer cells can evade apoptosis, which is a programmed cell death mechanism that eliminates damaged or abnormal cells. This allows cancer cells to survive and accumulate, contributing to tumor growth.

Normal Cells: Normal lung cells undergo apoptosis when they are damaged or no longer needed, ensuring proper tissue maintenance and homeostasis.

Invasion and Metastasis:

Cancer Cells: Cancer cells can invade surrounding tissues and spread to distant parts of the body through the bloodstream or lymphatic system, a process known as metastasis.

Normal Cells: Normal lung cells remain localized to their specific tissue and do not invade neighboring tissues or spread to other parts of the body.

Angiogenesis:

Cancer Cells: Cancer cells can stimulate the formation of new blood vessels (angiogenesis) to supply the growing tumor with nutrients and oxygen.

Normal Cells: Normal lung cells do not induce excessive angiogenesis unless needed for tissue repair or growth.

Cell Shape and Organization:

Cancer Cells: Cancer cells often have irregular shapes, sizes, and organization. They may form disorganized clusters within tumors.

Normal Cells: Normal lung cells have a specific and organized structure, contributing to the proper functioning of lung tissue.

Functionality:

Cancer Cells: Cancer cells do not perform the specialized functions of normal lung cells. Instead, they divert resources toward rapid proliferation.

Normal Cells: Normal lung cells carry out their specialized functions, such as gas exchange and mucus production, to maintain respiratory health.

These differences collectively contribute to the aggressive and destructive behavior of cancer cells compared to normal cells in lung tissue. Understanding these distinctions is crucial for developing targeted therapies that selectively target cancer cells while preserving the health and function of normal cells.

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kalyani tallapaka

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11y ago

cancer cells are cells that are damaged by smoke as they are spread and the normal cells are the unharmed cells unless even they have been attaked by smoke

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the dogs bullocks

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Q: How are cancer cells different from normal cells in the lung tissue?
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