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There is probably no problem with the concept of "madness" in this phrase - it is acting or thinking in a disjointed or insane manner.

The concept of "bout" is a bit more difficult to explain.

A bout is a short period of intense activity. Think of a bout in terms of a Wrestling or boxing bout. In terms of health a bout is a period where the illness (mental or physical) is actively at work fighting with the person's normal condition.

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