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Schistosomiasis is a disease caused by a parasitic treponeme of the Genus Schistosoma. These worms have a complex life cycle involving fresh water snails and humans. Humans become infected by swimming in water in which the Schistosomal larvae are residing. The larvae attach to the skin and bore through, entering the dermal veins. They move to the pulmonary vasculature. They migrate through the pulmonary vasculature to the portal vasculature where they mature into adult worms and mate.

Depending on the specific species of worm, they stay in the portal vasculature or migrate to the bladder where they begin to release eggs, which migrate through the bowel or bladder walls to be shed via the urine or feces. The eggs hatch in freshwater and go on to infect the snails, where they reproduce and are released again as larvae, to begin the life-cycle again.

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16y ago

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