What is the pathology of diabetes type 2?

Answer 1

In short-terms: Your body developes resistance to insulin. This resistance makes harder to get glucose into your cells, so the levels in blood rise above normal. It is related to obesity, sedentarism, high simple sugars diet, fried foods... It is a Chronic and Degenerative disease that can be treated and controlled but not cured.

Answer 2

The normal fasting blood glucose level is 80 to 100 mg per 100 ml. The post meal blood glucose level is up to 140 mg per 100 ml. You have five liters of blood in your body. Out of these five liters of blood, you have two liters of blood cells. So the blood plasma is about only three liters. 80 mg per 100 ml means 800 mg per liter. It comes to be 2400 mg per three liters. You have up to 140 mg of blood glucose in the blood. That makes 1400 mg per liter. In the three liters of plasma you have 4200 mg of the glucose that is present. Your brain is totally depends on the use of blood glucose for proper functioning. This means blood glucose fluctuates between very narrow range. The large quantity of blood glucose is used for daily physical activities and for the basal metabolism. This means the glucose is supplied to the body very much efficiently as per need of the body. One gram of glucose gives four Calories. The average adult may require up to 3000 Calories per day. These are supplied by oxidation of the glucose, amino acids and fats. When the post meal blood glucose level rise up to 180 mg per 100 ml, the condition is called as the borderline Diabetes.

Next part described is pathology and should be taken as my personal opinion.

It should not be taken as expert or standard medical text. So the blood glucose appears in the urine of the patient once it cross the thresh hold of 180 mg per 100 ml. I will call this condition as diabetes. Once the glucose comes in the urine, it draws water with it. Glucose can not be excreted in powder form by the kidney. In the first phase this phase lasts for few hours after the food intake or only after taking sugar or some sweet in the food.

This response of rise of sugar is associated with defective entry of the glucose in the cell. Insulin hormone is secreted by the endocrine part of the pancreas. Insulin facilitates entry of the glucose into the cell. There is progressive deficiency of the insulin in the blood, which leads to the diabetes type two.

There is high blood glucose level outside the cell. But the cells starve for the blood glucose. The condition becomes like, "Water water every where and not a drop to drink". The blood glucose level rises progressively. So that the fasting blood glucose level cross 180 mg per 100 ml. Now there is loss of much water via kidneys. So there is excessive urination. As a result patient has to drink excessive water to make for the water loss. The glucose does not enter the cells of hunger center. So the patient starts eating excessive food. There is craving for the sweet food specially. As a result patient becomes overweight. So a vicious cycle is established.

I have been thinking on diabetes for years together. I attribute the toxic effects of the diabetes to the loss of that excess water via kidneys. You lose excessive water through the kidneys. Water carries the precious minerals with it. What you know about the minerals is sodium, potassium, calcium and magnesium ions mainly. They can be and usually replenished via food and diet supplement. But you do not know all the trace elements those are used in the body. Few may be used in nano quantity and they may be performing the most vital function in the body. Loss of such minerals is most probably results in the damage that is caused in the diabetes. I am almost sure about the same. But I can not prove this statement. The organism is evolved in this earth that is full of elements. You do not know about the trace elements, those are selected by the body for proper functioning. What you have to do is use rock salt instead of the pure and processed common slat in the food. As per Wikipedia rock salt contains numerous trace elements. Rock salt is natural supplement and is not polluted one.

So coming back to the pathology of the diabetes. Transient passage of glucose after the food intake can be tackled by the kidneys very easily. I personally prefer to keep the blood level of glucose between 160 mg to 220 mg after the meal. It is very much dangerous to try to control the blood glucose level to the perfect normal range. Patient can land up in hypoglycemia at any given moment. The effects of the hypoglycemia is much more serious than the transient hyperglycemia. So it is better to keep the blood glucose level a bit up. Only nature can keep that blood glucose level to perfect normal level. It is better not to try to become God yourself.