What is the pathophysiology of DVT?

Answer 1

Deep vein thrombosis (DVT) is the formation of a blood clot, known as a thrombus, in the deep leg vein.

The deep veins that lie near the center of the leg are surrounded by powerful muscles that contract
and force deoxygenated blood back to the lungs and heart. When the circulation of the blood slows down due to illness, injury or inactivity, blood can accumulate which provides an ideal setting for clot formation.

Symptoms
•Discoloration of the legs
•Calf or leg pain or tenderness
•Swelling of the leg or lower limb
•Warm skin
•Surface veins become more visible
•Leg fatigue

Left untreated, a deep vein thrombosis (DVT) can break off and travel in the circulation, getting trapped in the lung, where it blocks the oxygen supply, causing heart failure. This is known as a pulmonary embolism, which can be fatal.