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How might monoclonal antibodies be useful in criminology wildlife management or archaeology?
In criminology, monoclonal antibiodies are useful in distinguishing adult serum stains from those of a fetus's or newborn's serum in cases of illegal abortion or infanticide. (A new method uses sensitive detection of α-fetoprotein AFP in the stains.) In wildlife magaement it can be used to determine and map animals with diseases. An example is rabies. Monoclonal antibiodies can be used in archeology to identify archeological disoveries.
Exciting New Treatments For Cancer And Autoimmune Diseases?
Antibodies are produced by the body's immune system when an infection occurs. Under normal circumstances, the antibodies that are produced recognize a broad range of targets, for example, different parts of a virus or bacteria. Each specific antibody is known as a clone, and the normal response to an infection is a polyclonal response, because many different specificities are represented.Polyclonal antibodies purified from animals are commonly used tool in biological research. However, the polyclonal nature of antibodies can be detrimental, as the exact specificity is unknown. In order to overcome these complications, scientists developed a method for generating monoclonal antibodies (mAbs), i.e., antibodies of a single specificity. Ultimately, the development of the technology for producing monoclonal antibodies resulting in the presentation of the 1984 Nobel Prize in Physiology or Medicine to Niels Jerne, Georges Kohler and Cesar Milstein.Immediately following the development of monoclonal antibodies, these reagents were primarily utilized as research tools. Subsequently, mAbs have been developed into important diagnostic tests including pregnancy tests, HIV screening tests, and cancer diagnostics.More recently, monoclonal antibodies have been developed for the treatment of a number of different diseases. Thus far, this type of biological therapy has been FDA-approved for the treatment of various cancers and autoimmune diseases as well as the prevention of rejection of transplanted organs.Monoclonal antibody treatment of cancer is effective because the antibody can be used to block pathways that drive the growth of the cancer cells or inhibit the ability of the tumor to drive the development of new blood vessels that are required to supply the growing tumor with nutrients. In the case of autoimmune disease, including multiple sclerosis, psoriasis, Crohn's disease and rheumatoid arthritis, monoclonal antibody therapies can block the cells that cause damage from entering the tissues they target or they can block the ability of the cells to function. Similarly, monoclonal antibodies can be used to prevent rejection of transplanted organs, a response that is driven by activation of the immune system.Monoclonal antibodies are an exciting new avenue of intervention for diseases that have traditionally been very difficult to treat. Research regarding this approach is ongoing, and new drugs are being approved frequently. For example, the FDA has approved two new monoclonal antibody drugs in the first quarter of 2011 alone, illustrating the rapid progress of this new tactic for treating chronic diseases.
What method of manufactured solutions do you recommend for optimizing production efficiency?
One recommended method for optimizing production efficiency is implementing lean manufacturing principles. This involves identifying and eliminating waste in the production process to streamline operations and improve overall efficiency.
What was the Production Budget for A Dangerous Method?
The Production Budget for A Dangerous Method was $20,000,000.
Who invented assembly-line method of production?
Henry Ford invented the assembly-line method of production
Which method is used to compute depletion?
Units of production method.
When did Henry ford create the Assembly-line method of production?
Henry Ford invented the assembly -line method of production in 1913
What manufacturing method was used by Henry ford?
Assembly-line method of production.
What are the 4ms in production?
Money, Materials, Method, Man
The most common method of recording depletion for accounting purposes is the?
Units-of-production method.
Which or the following decontamination method is not recommended for removing vesicants from casualties?
Decontamination by washing with soap and water is not recommended for removing vesicants from casualties. This method can spread the vesicant agent further and should be avoided. Instead, the recommended method is to use specific decontamination solutions and procedures designed for vesicants.
What is a lifo method?
In Lifo method goods received in last are used first in production that is means by last in first out method.
