When the blood glucose level exceeds about 160 - 180 mg/dl (8.9 - 10 mmol/l), the proximal tubule becomes overwhelmed and begins to excrete glucose in the urine. This point is called the renal threshold of glucose (RTG) hope that this answer might help you and it is taken from wikipedia.
Renal threshold is what happens when there is an overabundance of glucose in the body, the blood glucose levels will then get above 170mg/100ml (normal is 70mg/100ml).
it shows in urine.
It will cause the change of the alpha and beta cells
Charles Beaverstock has written: 'Effect of renal threshold on urine glucose and patient acceptance and maintenance of home blood glucose monitoring'
Type your answer here... It is nothing but surpassing the renal threshold of an individual above the threshold which was normal to that person in certain period.
Glucose reabsorption in the kidneys prevents it from being excreted in urine. This reabsorption process occurs in the renal tubules, where glucose is actively transported back into the bloodstream. If blood glucose levels are too high, such as in diabetes, the renal threshold for glucose reabsorption may be exceeded and glucose can then be excreted in the urine.
First of all, WHAT KIND OF QUESTION IS THAT?But, whatever. The renal threshold, where glucose levels exceeds the capacity to return the glucose into the blood (glycosuria) is about 10 mmol/l (180 mg% ).
In a healthy person, urine does not contain glucose because the kidneys efficiently reabsorb glucose from the filtrate back into the bloodstream during the process of urine formation. This reabsorption occurs in the proximal convoluted tubule, where glucose is transported alongside sodium ions. Only when blood glucose levels exceed a certain threshold (as seen in conditions like diabetes) does glucose appear in the urine, indicating that the renal threshold for glucose reabsorption has been surpassed.
Glucose is typically reabsorbed in the kidneys primarily through the sodium-glucose co-transporter (SGLT) in the proximal tubule. This active transport mechanism allows glucose to be reabsorbed back into the bloodstream, preventing its loss in urine. In healthy individuals, the renal threshold for glucose is such that it is fully reabsorbed until blood glucose levels exceed this threshold, leading to glucose appearing in urine. Additionally, hormonal regulation, particularly by insulin, helps maintain normal glucose levels in the blood.
Glycosuria is primarily caused by elevated blood glucose levels, which can occur in conditions like diabetes mellitus when the renal threshold for glucose reabsorption is exceeded. Other potential causes include kidney disorders that affect glucose reabsorption, hormonal imbalances, or the use of certain medications. In some cases, glycosuria may also be seen in pregnancy due to increased renal blood flow and changes in glucose metabolism.
Glycosuria occurs when there is an excess of glucose in the blood that exceeds the renal threshold for glucose reabsorption, typically around 180 mg/dL. This can happen in conditions like uncontrolled diabetes mellitus, where insulin deficiency or resistance leads to elevated blood glucose levels. When the kidneys cannot reabsorb all the glucose filtered through them, the excess glucose is excreted in the urine. Other causes of glycosuria can include renal tubular disorders or certain hormonal imbalances.
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