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While some types of aortic dissections do not require emergent surgery, the majority do. An aortic dissection is a serious and life-threatening condition. The decision regarding appropriate treatment should be made in consultation with an experienced surgeon who specializes in the treatment of aortic disease.

If the dissection is acute--occurring less than 2 weeks prior-- and involves the more proximal portions of the aorta, (eg, the root, ascending aorta, or aortic arch), emergent surgery is generally required. If the dissection involves the more distal aorta (eg, descending thoracic aorta or abdominal aorta), strict blood pressure is typically recommended. Surgery may be recommended for dissections of the distal aorta when it is believed to be the cause of ongoing back or abdominal pain, renal damage, paralysis, bowel ischemia, limb ischemia, or aortic rupture. Surgery may also be recommended when the aorta is significantly enlarged.

If an aortic dissection is found (or suspected), strict blood pressure control is needed with a target mean arterial pressure of 60-75 mmHg. Beta blockers (e.g. Esmolol, Propranolol, or Labetalol) are first-line treatment. Calcium-channel blockers (e.g. Verapamil and Diltiazem) can be used, particularly if there is a contraindication to beta blockers. Vasodilators (e.g. Sodium nitroprusside) can be used for refractory hypertension, but they never should be used without beta- or calcium-channel blockers. Vasodilators, including Hydralazine and Minoxidil, and beta-blockers that have intrinsic sympathomimetic action (e.g. Acebutolol, Pindolol) should be avoided.

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