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A strong promoter is characterized by its ability to effectively initiate transcription, often due to specific DNA sequence elements that facilitate the binding of RNA polymerase and transcription factors. Factors such as a high affinity for these proteins, the presence of enhancer regions, and a favorable chromatin structure contribute to its strength. Conversely, a weak promoter may lack these features, leading to inefficient transcription initiation and lower gene expression levels. Additionally, mutations or epigenetic modifications can also impact promoter strength.

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1mo ago

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