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Leukemia primarily affects the blood and bone marrow, but it can also spread to other areas of the body, including the lymph nodes, liver, spleen, and central nervous system. In advanced stages, leukemic cells may infiltrate various organs, leading to complications in their function. Additionally, leukemia can cause extramedullary manifestations, where cancerous cells appear in tissues outside the bone marrow. Early detection and treatment are crucial to managing the spread of the disease.

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