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In children with Adrenoleukodystrophy (ALD), the malfunctioning part of the brain that can contribute to tantrums is primarily the frontal lobe, which is responsible for impulse control, emotional regulation, and decision-making. Additionally, the limbic system, particularly the amygdala, plays a role in processing emotions, and its dysfunction can exacerbate emotional outbursts. The progressive degeneration of white matter in ALD affects these areas, leading to behavioral challenges and tantrums.

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1mo ago

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