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Syphilis can be cured with antibiotics, but many people don't notice the early symptoms. It can lead to nerve damage, blindness, paralysis, and even death over time if not treated. The first sign is typically a painless sore on the genitals or anal area. It is usually round and firm. A rash can develop later on the soles of the feet, palms, or other parts of the body. Other symptoms can include enlarged lymph nodes, fever, fatigue, or hair loss. Late-stage syphilis can cause damage to many different organ systems.

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