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Granular leukocytes, or granulocytes, arise from myeloid precursor cells in the bone marrow. Specifically, they differentiate from common myeloid progenitor cells into myeloblasts, which further develop into promyelocytes, myelocytes, metamyelocytes, and eventually mature into neutrophils, eosinophils, or basophils. This process is regulated by various growth factors and cytokines that promote their maturation and development.

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