Calcified bone is composed of approximately 30% organic material, primarily collagen, along with various proteins and carbohydrates. The remaining 70% is primarily inorganic minerals, mainly hydroxyapatite, which provides bone its strength and rigidity. This unique composition allows bones to be both strong and resilient while maintaining some flexibility.
The process that breaks down the calcified matrix is primarily carried out by cells called osteoclasts. These cells resorb bone tissue by dissolving the mineral components and degrading the organic matrix. Once the calcified matrix is broken down, it is replaced by bone-building cells known as osteoblasts, which synthesize new bone matrix and facilitate bone formation. This dynamic process is essential for bone remodeling and maintenance.
former osteoblasts that have become surrounded in bone matrix that is calcified
Increasing the proportion of organic molecules in the bony matrix would likely make the bone more flexible and less brittle. This is because organic molecules provide elasticity and strength, while inorganic components like minerals provide hardness and rigidity. Balancing these components is important for maintaining the structural integrity of bone.
First of all, who is it that 'believes' this lump on your forehead is 'calcified bone'? If it was you or other persons who don't have a medical license, see a doctor. If your doctor believes the lump to be calcified bone, ask your doctor what should be done to remove it.
The matrix of the bone (calcified hydroxyapatite) is non-living; the living part of the bone are the cells (osteoblasts, osteocytes, osteoclasts) and the periosteum, a tough membrane that covers the bone and allows tendons and ligaments to attach to the bone.
Opacification means to become opaque - not see-through/transparent.
Osteoporosis is a serious bone disease characterized by excessive loss of both calcified matrix and collagenous fibers, leading to weaker, more brittle bones that are at a higher risk of fractures. It is often associated with aging, hormonal changes, and nutritional deficiencies.
Calcified cartilage is a type of cartilage that has undergone a process of mineralization, where calcium salts are deposited within its matrix. This transformation typically occurs in the transition zone between hyaline cartilage and bone, particularly during endochondral ossification in developing bones. The presence of calcified cartilage provides structural support and serves as a precursor to bone formation, playing a crucial role in skeletal development and growth. Unlike regular cartilage, calcified cartilage is less flexible and more rigid due to its mineral content.
A typical bone has an outer layer of hard or compact bone, which is very strong, dense and tough. Inside this is a layer of spongy bone, which is like honeycomb, lighter and slightly flexible. In the middle of some bones is jelly-like bone marrow, where new cells are constantly being produced for the blood.
Calcified opacity is a radiological word that means there was an opaque area in rays that could not penetrate and just appear like a bone. This also means that the light does not pass though the material being described.
The bone matrix is made of 35% organic material and 65% inorganic materials. The organic material gives bone flexibility & strength.
spongey bone is flexible but can break very easily. Isnt science fascinating.