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In the ABO blood group system, a person's immune system naturally creates antibodies to the antigens that it lacks.

Group A people have the A antigen, so they will make Anti-B.

Group B people have the B antigen, so they will make Anti-A.

Group O people do not have A or B antigens, so they make both Anti A and Anti B.

Group AB people have both A and B antigens. They do not have antibodies in this blood group system.

So, the short answer to your question: B and O people will both have Anti-A in their blood.

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