In the seventh week of the embryo's development
Ossification, the process of bone formation, typically begins with the development of a cartilage model during fetal development. This process, known as endochondral ossification, starts around the second month of gestation and continues until early adulthood. The primary ossification centers form in long bones, followed by secondary centers in the epiphyses. Eventually, ossification concludes when the growth plates (epiphyseal plates) close, which occurs in late adolescence to early adulthood, solidifying the bone structure.
epipheal plates
When osteoblasts begin to differentiate within a connective tissue, the process is called osteogenesis or ossification. This process involves the formation of new bone tissue through the secretion of extracellular matrix components by osteoblasts.
Endochondral ossification
ossification
Intramembranous ossification
ossification
Intramembranous and Endochondral Ossification
Ossification (or osteogenesis) is the generic term for bone formation. There are two basic types: membranous ossification and endochondral ossification.
Ossification occurs when bones are formed.
Intramembranous ossification