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The allele responsible for sickle-cell anemia can be found on the short arm of chromosome 11, more specifically 11p15.
The sickle-cell disease occurs when the sixth amino acid, glutamic acid, is replaced by valine to change its structure and function. Sickle-cell anemia is also known as E6V.
Valine is hydrophobic, causing the hemoglobin to collapse on itself occasionally. The genetic disorder is due to the mutation of a single nucleotide, from a GAG to GTG codon on the coding strand, which is transcribed from the template strand into a GUG codon.
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Is sickle cell anemia an autoimmune disease?
Sickle Cell Anemia is Autosomal Recessive. It arises from a mutation on the beta-globin gene of chromosome 11. Because Sickle Cell Anemia is an example of incomplete dominance, a person has the disease if they have two mutated beta-globin genes but only has the trait (is a carrier) if they have only one mutated beta-globin gene.
Is sickle cell disease autosomal or x-linked or chromosomal?
Sickle cell is a sex-linked trait, If some one is a carrier than the trait is passed down on that chromosome.
Is caused by a mutated allele that produces a defective form of the protein hemoglobin.?
False, Sickle Cell Disease :))
Hemophilia is caused by a mutated allele that produces a defective form of the protein hemoglobin?
False, Sickle Cell Disease :))
Is sickle cell anemia x-chromosome or non x-chromosome?
Sickle cell anemia is not sex linked.
Is you kiss do you get sickle cell disease?
No. Sickle Cell is not an infectious disease, but is genetic.
Is sickle cell disease a blood cancer?
No, sickle cell disease is not cancerous.
The genetic disorder sickle cell disease is an example of heterozygous dominance?
Yes. Heterozygous dominance offers a way to preserve the mutated allele.
What chromosome number is affected in sickle cell disease?
Christian Dutton has gunneria and will be a virgin for life.
What genetic disorder results in abnormally shaped blood?
Spherocytosis
How can sickle-cell disease be treated?
Stem cell or bone marrow transplants are the only cure for sickle cell disease
What is the causative agent of sickle cell?
Sickle cell disease is caused when someone inherits sickle shaped hemoglobin. It is a disease that can be managed, but not cured.
