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Is sickle cell anemia x-chromosome or non x-chromosome?
Sickle cell anemia is not sex linked.
Who is affected by sickle cell anemia?
Sickle cell anemia is a genetic blood disorder affecting individuals who inherit two copies of the abnormal hemoglobin gene from both parents. This primarily affects people of African, Mediterranean, Middle Eastern, and South Asian descent.
What are other names for sickle cell anemia?
Hemoglobin SS disease (Hb SS)
Does sickle cell disease require two allele or multiple alleles?
Sickle cell disease is an autosomal reccessive sexlinked trait so, a female msut have 2 recessive alleles to have the trait and a male needs only one allele (this is because there is no corresponding site for this allele on the Y chromosome. The female can be a carrier of the disorder with the defective allele on one X chromosome and a normal allele on the other X chromosome. Female carrriers can have a mixture of normal and abnormal redblood cells.
What genetic disorder results in abnormally shaped blood?
Spherocytosis
Is sickle cell disease autosomal or x-linked or chromosomal?
Sickle cell disease is an autosomal recessive disorder, meaning that it is caused by a mutation in one of the autosomal chromosomes (chromosomes that are not sex chromosomes). In the case of sickle cell disease, the mutation occurs in the gene encoding the beta-globin subunit of hemoglobin on chromosome 11.
What gene or chromosome is mutated in sickle cell disease?
The allele responsible for sickle-cell anemia can be found on the short arm of chromosome 11, more specifically 11p15.The sickle-cell disease occurs when the sixth amino acid, glutamic acid, is replaced by valine to change its structure and function. Sickle-cell anemia is also known as E6V.Valine is hydrophobic, causing the hemoglobin to collapse on itself occasionally. The genetic disorder is due to the mutation of a single nucleotide, from a GAG to GTG codon on the coding strand, which is transcribed from the template strand into a GUG codon.
Is sickle cell anemia x-chromosome or non x-chromosome?
Sickle cell anemia is not sex linked.
How is sickle cell anemia inherited?
This is inherited on the X chromoseome and is recessive. This means a female (who has XX chromosome pair) can only express the disease if she carries the trait on both chromosomes. This is because of the recessive nature of the gene. A male can only inherit the disease from his mother. This is he must have obtained his Y chromosome from his father so he obtains the X chromosome from his mother. A male cannot carry the gene without expressing it as he doesnt have another X chromosome to supress the recessive gene. ^ This answer is biologically incorrect because Sickle cell Anemia is actually autosomal recessive, not sex-linked recessive; this means that males and females are affected equally and it is NOT carried on the X chromosome. In order for the trait to show up in an individual, BOTH parents must be carriers of the disease (at least 1 sickle cell gene must be present).
Is sickle cell anemia an autoimmune disease?
Sickle Cell Anemia is Autosomal Recessive. It arises from a mutation on the beta-globin gene of chromosome 11. Because Sickle Cell Anemia is an example of incomplete dominance, a person has the disease if they have two mutated beta-globin genes but only has the trait (is a carrier) if they have only one mutated beta-globin gene.
What are the common example of aneuploiy?
aneuploidy.Aneuploidy is an abnormal number of chromosomes, and is a type of chromosome abnormality. An extra or missing chromosome is a common cause of genetic disorders (birth defects).Some genetic disorders are polycystic kidney disease / sickle cell anemia / hemophilia.This comes from wikipedia
What is the probability of am man and woman giving birth to a child who to is sickle cell like both of them?
If both parents are carriers of the sickle cell trait (genotype AS), there is a 25% chance that their child will inherit the sickle cell disease (genotype SS). Each parent has one normal hemoglobin allele (A) and one sickle cell allele (S), which means the possible combinations for their child are AA, AS, and SS. Therefore, the probability of the child being affected by sickle cell disease is 25%. If both parents have sickle cell disease (genotype SS), then all children will also be affected (100%).
Who is affected by sickle cell anemia?
Sickle cell anemia is a genetic blood disorder affecting individuals who inherit two copies of the abnormal hemoglobin gene from both parents. This primarily affects people of African, Mediterranean, Middle Eastern, and South Asian descent.
What population is affected by sickle cell disease?
Sickle cell generally affects those of African origin, more specifically those whose parents are from areas where malaria is common
Is Sickle cell anemia inherited?
This is inherited on the X chromoseome and is recessive. This means a female (who has XX chromosome pair) can only express the disease if she carries the trait on both chromosomes. This is because of the recessive nature of the gene. A male can only inherit the disease from his mother. This is he must have obtained his Y chromosome from his father so he obtains the X chromosome from his mother. A male cannot carry the gene without expressing it as he doesnt have another X chromosome to supress the recessive gene. ^ This answer is biologically incorrect because Sickle cell Anemia is actually autosomal recessive, not sex-linked recessive; this means that males and females are affected equally and it is NOT carried on the X chromosome. In order for the trait to show up in an individual, BOTH parents must be carriers of the disease (at least 1 sickle cell gene must be present).
Is sickle cell disease a blood cancer?
No, sickle cell disease is not cancerous.
Is you kiss do you get sickle cell disease?
No. Sickle Cell is not an infectious disease, but is genetic.
