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London was severely affected by both the Great Plague and the Great Fire in the mid-1660s. The Great Plague, which peaked in 1665, resulted in the deaths of an estimated 100,000 people, significantly reducing the city's population. In September 1666, the Great Fire of London broke out, destroying a large portion of the city, including thousands of homes and numerous landmarks. These two catastrophic events had a profound impact on London's history and development.

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