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What is a Cox-2 inhibitor?
Cox-2 inhibitors are non-steroidal anti-inflammatory drugs (NSAIDs) which selectively inhibit cyclooxygenase-2.
What is an antiplatelet?
Antiplatelet drugs interact with platelets, which is a type of blood cell, to block platelets from aggregating into harmful clots.
Drugs act on the neurons in the reward pathway or the?
Drugs act on the neurons in the limbic system.
Where can one find information about Cyclooxygenase?
Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to prostaglandins was first identified over 20 years ago. Drugs, like aspirin, that inhibit cyclooxygenase activity have been available to the public for about 100 years. In the past decade, however, more progress has been made in understanding the role of cyclooxygenase enzymes in biology and disease than at any other time in history. Two cyclooxygenase isoforms have been identified and are referred to as COX-1 and COX-2. Under many circumstances the COX-1 enzyme is produced constitutively (i.e., gastric mucosa) whereas COX-2 is inducible (i.e., sites of inflammation). Here, we summarize the current understanding of the role of cyclooxygenase-1 and -2 in different physiological situations and disease processes ranging from inflammation to cancer.
Will Motrin cause bleeding if you have low platelets or a platelet problem?
Motrin (ibuprofen) and other medications in the class of non-steroidal anti-inflammatory drugs (NSAIDs) affect platelet aggregation (decrease the ability of platelets to clump together and form clots). Therefore, Motrin can cause bleeding if you have low platelets or your platelets don't function properly.
What is the sentences for pathway?
His use of drugs and alcohol led him on a pathway to depression.
Which classification of drugs includes general local and nerve blocks?
Anesthesia is the drug class that includes local, general, and nerve blocks.
What is cox1 and cox2 and cox3?
Cox1, Cox2, and Cox3 refer to different isoforms of cyclooxygenase enzymes, which are involved in the conversion of arachidonic acid to prostaglandins, compounds that mediate inflammation and pain. Cox1 (cyclooxygenase-1) is constitutively expressed and plays a key role in maintaining normal physiological functions, such as gastric protection and platelet aggregation. Cox2 (cyclooxygenase-2) is inducible and associated with inflammation and pain, making it a target for anti-inflammatory drugs. Cox3 is a less well-defined isoform, primarily studied in the context of the central nervous system, and is thought to be involved in pain perception but is less understood compared to Cox1 and Cox2.
Why do you bleed a lot from small cuts?
Prolonged bleeding can be caused by problems with the platelets count or platelets function. Certain drugs can also cause prolonged bleeding such as blood thinners.
Which chemical pathway appears to be important both in some types of psychotic behavior and in the reinforcing properties of various drugs?
Mesolimbic Dopamine
Which is an effect of psychoactive drug abuse?
A psychoactive effect is an affect on mood or behavior caused by the misuse of drugs.
When drugs produce a sensation of well being what part of the brain is being stimulated?
Drugs that produce a sensation of well-being typically stimulate the brain's reward pathway, which includes areas such as the nucleus accumbens and the ventral tegmental area. This pathway is involved in the release of dopamine, a neurotransmitter associated with pleasure and reinforcement of rewarding behaviors.
