not within the synaptic CLEFT (gap) itself, across which neurotransmitters diffuse, but yes, in the axon & axon terminal leading up to the synapse, and in the dendrite coming from the synapse.
Neurotransmitters are stored in synaptic vesicles called the presynaptic terminal. These vesicles are located at the end of the axon terminal of a neuron and release neurotransmitters into the synapse to facilitate communication with other neurons.
They are called as vesicles. They are constantly created. They contents the neurotransmitter. Neurotransmitter is required for transmission of the nerve impulse.
evolution
Tone denotes the concentration of neurotransmitter within a given region of the nervous system. A lot of glutamate indicates a high excitatory, glutamatergic tone.
medulla oblongata
Criteria required identifying a substance as a neurotransmitter 1- ) Synthesis of the substance: • It is synthesized in the neuron • Some substances are synthesized from the Tryptophan • Rate limiting step in its synthesis • Enzymes required in the synthesis of that substance are themselves synthesized in the cell body of neuron ,then distributed throughout the neuron • Mainly found in the cell body and nerve terminal • These enzymes are stored in the presynaptic terminal of neuron, inside the synaptic vesicles. 2- ) Storage of that substance: • The neutransmitter is stored inside the synaptic vesicle of nerve terminal 3- ) Release of the neurotransmitter: • It is released from the nerve terminal usually through Ca++ dependent process following the stimulation of the nerve fiber by action potential. • Fusion of the synaptic vesicle with the nerve membrane releasing neurotransmitter outside the nerve fiber into the synaptic cleft. 4- ) Exogenous analogue (drug) of the neurotransmitter: • If drug analogue of the neurotransmitter is injected exogenously, it should mimic the same mechanism of action as done by the endogenously released neurotransmitter.
Acetylcholine
Synaptic vesicles containing neurotransmitters play a crucial role in communication between neurons. They release neurotransmitters into the synaptic cleft, where they bind to receptors on the receiving neuron, leading to signal transmission. This process allows for the relay of information within the nervous system.
The water table
The presence of an enzyme called acetylcholinesterasethat degrades acetylcholine is what prevents an accumulation of the neurotransmitter and sustained muscle contraction. Acetylcholinesterase is an enzyme that can be found within the neuromuscular junction. Thus, when a nerve impulse causes the release of acetylcholine at the neuromuscular junction, there is a critical time in which the neurotransmitter can bind to receptors on the muscle before it is degraded.
The Choroid.