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It neurons but nova net wants muscles
In Parkinson's disease, the substantia nigra region of the brain deteriorates, leading to a decrease in dopamine production. This reduction in dopamine can cause problems with movement and coordination, resulting in symptoms like tremors, rigidity, and bradykinesia. Additionally, Lewy bodies, abnormal protein clumps, can accumulate in certain brain cells, contributing to the progression of the disease.
A result of repeated blows to the head during his boxing career
Severe shaking is the most apparent symptom of Parkinson's disease. This coarse tremor features four to five muscle movements per second. These movements are evident at rest but decline or disappear during movement.
Parkinson's disease is an illness that affects nerve cells in the brain, especially dopamine-producing neurons. When dopamine levels decrease, it causes abnormal brain activity, leading to impaired movement and other symptoms of Parkinson's disease. Its causes are unknown but factors that can affect this disease are Genes: Researchers have found that some people with many family members affected by Parkinson's disease have mutations in the LRRK2 gene. The presence of these gene variations can increase a person's risk for Parkinson's disease but only slightly. Therefore, genetic testing cannot predict who will or will not develop Parkinson's disease. Environment: Being exposed to certain toxins or environmental factors, especially during a vulnerable time such as childhood, may cause the development of Parkinson's disease. However, this is considered to be a minor factor in this disease.
Very poor i believe he had Parkinson's Disease from 1933 so i say he was very unstable indeed
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Perhaps. She steadfastly denied that she suffered from the disease: http://www.imdb.com/name/nm0000031/bio Quote: "Now to squash a rumor. No, I don't have Parkinson's." However, tremors were quite obvious in her movies and appearances during the last 30-40 years of her life. The BBC reported that she suffered from Parkinson's at the time of her death and, while her medical records are not available to the public, it is commonly believed that she indeed suffered from the disease and coped with its symptoms without medication: http://news.bbc.co.uk/2/hi/3030792.stm
Patients with advanced Parkinson's disease may move rapidly during an emergency due to a phenomenon known as kinesia paradoxica. This is a sudden and temporary improvement in mobility and coordination that can occur in response to a stressful or urgent situation. The surge of adrenaline and other stress hormones released during an emergency can temporarily override the typical movement difficulties associated with Parkinson's disease, allowing the patient to move more quickly and efficiently. However, it is important to note that this burst of mobility is often short-lived and does not indicate a permanent improvement in the underlying condition.
MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is a neurotoxin that causes permanent symptoms of Parkinson's disease by killing certain neurons in the substantia nigra of the brain. It is used to study the disease in monkeys. While MPTP itself does not have opioid effects, it is related to MPPP, a synthetic opioid drug with effects similar to those of heroin and morphine. MPTP can be accidentally produced during the illicit manufacture of MPPP, and that is how its Parkinson-inducing effects were first discovered.
Tremors are uncontrollable quivering movements or shakes. The hallmark slow, rhythmic tremor of Parkinson's disease usually begins in one hand, foot, or leg and progresses to both sides of the body. Parkinson's disease resting tremors might affect the jaw, chin, mouth, or tongue. Furthermore, some persons with Parkinson's disease may suffer an inward tremor that is not always visible to others. Tremor is a common symptom of Parkinson's disease. It affects around 80% of Parkinson's patients. Although many people, including those with Parkinson's disease, believe that tremor is the primary symptom of the disease, it isn't—at least not for most people. Tremor is not debilitating for most people with Parkinson's disease. Tremor, on the other part, is unpleasant. It also draws attention, causing many to hide their terrible hand in their pocket or sit on it during meetings. Tremor does not appear to impede significantly with daily tasks because it disappears with movement. What makes a Parkinson’s tremor different? The tremor that occurs in Parkinson's disease is distinct from practically all other tremors in that it is a "resting tremor," meaning it only occurs while the patient is at rest. It fades away with movement but comes back when the limb (typically a hand or fingers) is held in one position, such as while putting a spoon or fork to the mouth, which is why people with Parkinson's are prone to spilling objects. Tremors caused by Parkinson's disease can affect practically any region of the body, although the fingers are the most usually affected, followed by the hands, jaw, and feet in that order. Finger Twitching : The "pill-rolling" tremor, which is frequently mentioned in medical publications, refers to tremors of the fingers, mainly the thumb and other fingers, that make it appear as if the person is rolling a pill in his or her fingers. Tremors are most commonly started in this area of the body. Jaw Tremors: While head tremor is widespread in Parkinson's disease, jaw tremor is uncommon. The jaw tremor resembles shivering, but it is usually slower. It vanishes with movement, so it's not noticeable while eating. When it is severe enough to force the teeth to click together, it is exceedingly irritating. It may prevent dentures from keeping in place for persons who wear them, as well as attracting attention due to the clicking sounds. The tremor is relieved by chewing gum. Foot Tremors: Many, if not all, persons can get a leg tremor if they rest their leg in certain situations with their heel slightly off the ground. This isn't a tremor caused by Parkinson's disease. A foot tremor caused by Parkinson's disease is a resting tremor, which means it is most noticeable while the feet are dangling or when the person is lying down. It always goes away when the person stands up (those who shake when they stand up have a separate issue), and it doesn't stop them from walking. The tremor mainly affects the feet, but it can also affect the thighs, causing the entire leg to move. Tongue Tremor: The tongue can tremble sometimes, and the head shakes in roughly 1% of Parkinson's disease cases. The head tremors occasionally as a result of the arms shaking, and the tremor is simply transmitted. While the voice is usually affected by Parkinson's disease, it is never affected by tremor. Read more about Parkinson's disease's vocal effects. Prognosis: Those with Parkinson's disease who have tremor as their primary symptom (rather than slowness, stiffness, or walking issues) appear to have a considerably more benign course than others. They progress at a slower pace and are likely to live longer. It also appears that tremor is the only sign of Parkinson's disease that can improve on its own; some people with severe tremors have seen their tremors almost vanish over the course of a decade. Tremors also rarely get worse after a certain point; at some time, the tremor will stop getting worse. Of course, no one can say when that will happen or how serious it will be.