People who are overweight, inactive and have a family history are at an increased risk for type 2 Diabetes. Certain races, those over 45 and women who have had gestational diabetes are also at an increased risk for type 2. For type 1 diabetes, those who have a family history, the presence of certain genes, and some geographical areas have an increased risk.
BRCA1 mutation is a genetic alteration in the BRCA1 gene that increases the risk of developing breast and ovarian cancer. Individuals with a BRCA1 mutation have an increased likelihood of developing these types of cancer compared to those without the mutation. Testing for BRCA1 mutations can help in assessing cancer risk and guiding management options.
Part of the risk factors for developing MS include genetics, but the risk of developing MS is not all influenced by genetics. The average risk of a person in society developing MS is 1 in 750. But if you have first-degree relatives (parents, siblings, etc.) who have MS, then your risk increases to anywhere between 1 in 100 to 1 in 40. But it is not all genetic. You can see this through the "identical twin" example. If you had an identical twin (same DNA structure, etc) who had MS, your risk of developing MS would be 1 in 4. If genetics were completely responsible for determining MS risk, your risk should be 100%. The fact that your risk is only 25% shows that there are other factors involved in determining your risk; ethnicity, geography, sex, and an as-of-yet undiscovered environmental "trigger" (such as a common disease), all of which play into your risk of developing MS.
Yes and no. If you exercise and stay in healthy weight, you will most likely not be inherited. However, the risk factors are inherited, because if you are overweight and do no exercise, you may be at risk for getting type 2 diabetes more than a regular person only if type 2 diabetes runs in the family.
I don't remember the source of this info, but I read somewhere that the general risk of type 1 DM in the general public is roughly 0.5%. If the father has Type 1, then the risk for any given child is about 8%. If the mom has it, then the risk is about 5%. If both have it, the risk is around 16% or so. Like most things in medicine, there is a genetic component to type 1 diabetes, and thus an increased chance that your children could develop it. But I wouldn't let that stop you from having children. If you have a child with diabetes, at least you already know about it and how to deal with it.
The most serious risk is an increased hearing loss, which occurs in about 1% of patients. Because of this risk, a stapedectomy is usually performed on only one ear at a time.
No. However, there is extensive medical research evidence that drinking alcohol in moderation reduces the risk of developing type 2 (adult-onset) diabetes. You do not catch diabetes, it is not infectious. It is thought that a persons genes can influence their risk of developing diabetes but no one gene can predict its development. A combination of genetic risk and environmental factors are thought to be needed to trigger diabetes. When looking at identical twins, if one twin has Type 1 diabetes, the other twin will have roughly a 50% chance of developing the disease. The trigger could be a trauma ie illness or accident or something like that. Type 2 can be due to over weight or unfit but also normal weight, normally adults, can get type 2. They are different conditions but are treated similarly. Type 1 sufferers automatically need insulin injections or via a pump and type 2 only sometimes need extra insulin, other times it is dealt with by diet and/or tablets. Type 2 is even more strongly linked to genetics and family history than type 1 diabetes. A family history of type 2 diabetes and obesity are the main risk factors in type 2 diabetes.
This will reduce the type 1 error. Since type 1 error is rejecting the null hypothesis when it is true, decreasing alpha (or p value) decreases the risk of rejecting the null hypothesis.
Yes they can but not as easily. Recent studies have shown that DNA damage caused by diabetes can result in less viable spermatazoa, increasing genetic weakness possibly contributing to an increased risk of miscarriage.
A simple risk assessment can be done by asking the following 2 questions 1) How likely is the incident to occur; and 2) How serious would the consequences be if it did occur and working it out from there..
"Dyslipidemia" refers to any of several lipid abnormalities. Lipid abnormalities can be divided into 3 categories: 1. High Cholesterol. This refers to high LDL (low-density lipoprotein). 2. Low HDL. Your "good cholesterol" (high-density lipoprotein) should not be too low. 3. High Triglycerides. Triglycerides are fat which are not cholesterol. All 3 of these abnormalities put one at increased risk of having a heart attack. Both Low HDL and High Triglycerides put one at increased risk of developing diabetes.
A combination of factors increase the risk of a Type 1 error. Giving the wrong amount or wrong diagnosis for a wrong drug would certainly increase an error.
if the chances of winning the lottery are 1 in a 1000 and you buy 1000 tickets you have a very very good chance of winning the lottery. with CVD there aren't 1000 risk factors