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Current first line treatments for HSV-1 (Herpes Simplex Virus type I, usually in the mouth region) and HSV-2 (Herpes Simplex Virus type II, usually in the genital region) are Acyclovir, Valacyclovir and Famcicolovir. These drugs are nucleoside analogs. Their method of action is to prevent the production or new viral genetic material by inserting themselves into the viral DNA and terminating synthesis. Therefore, they are only functional against stopping the production of new viruses. These drugs cannot kill existing viruses lying dormant in the neuron. Currently no drug exists to kill dormant (non-replicating) HSV-1 or HSV-2 in the body.

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13y ago

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