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ACE-inhibitors cause an increase in bradykinin, this can cause a dry cough in some patients.

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15y ago

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How long does it take to get rid of a cough after stopping ace inhibitors?

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What is the most troublesome side effect of ace inhibitors?

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Some anti-hypertensive medications do cause a cough. At first there is the sensation of a tickle at the back of the throat, and then a cough which feels as though it will clear this. However, for some individuals (single digit percentages), this cough becomes chronic and annoying. Lisinopril and other anti-hypertensive medications in the class of ACE (angiotensin converting enzyme) inhibitors is best known for producing this effect. Benicar has been reported to cause such a cough, in isolated cases. So, yes, it is possible, although rare.


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Which category of blood pressure medication is most likely to cause annoying dry cough as a side effect?

Angiotensin-converting enzyme (ACE) inhibitors are the category of blood pressure medications most likely to cause a dry cough as a side effect. This occurs in a subset of patients due to the accumulation of bradykinin, a substance that can irritate the respiratory tract. If a patient experiences this side effect, healthcare providers may consider switching to an angiotensin II receptor blocker (ARB), which typically does not cause cough.


Why should ACE inhibitors not be used by pregnant women?

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