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When a kidney stops functioning, it undergoes a process called atrophy, where the tissues begin to shrink due to a lack of blood flow and reduced demand for filtration. The loss of functional nephrons, the kidney's filtering units, leads to decreased workload and can cause cellular changes that contribute to shrinkage. Additionally, the accumulation of waste products and toxins can further damage kidney tissue, exacerbating the atrophy. This process is often seen in chronic kidney disease or after acute kidney injury.

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1w ago

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