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Between T3 and T4, T3 is the bioavailable form of the hormone which the body is able to actively utilize to control metabolism. T4 is only storage hormone, making it a less reliable predictor of current metabolic functions since it must first be converted. Some patients are unable to convert T4 to T3 effectively. Totals are less reliable than Frees however, so between the two hormones, the most reliable hormone to test is Free T3, not Total T3. That said, diagnosing thyroid dysfunction requires multiple tests for appropriate diagnosis, since the overall impression is most important in the diagnostic process, not a single hormone.

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12y ago

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