Isoniazid is a first line anti-tubercular drug which is used in treatment of tuberculosis.
Pyridoxine is the naturally occurring form of vitamin B6. Following absorption from the gastrointestinal tract, it is converted in the liver to a coenzyme, pyridoxal phosphate, that is involved in many metabolic processes. Isoniazid interferes competitively with pyridoxine metabolism by inhibiting the formation of the active form of the vitamin, and hence often results in peripheral neuropathy.
Hence, to prevent peripheral neuropathy, pyridoxine 10mg/day is given prophylactically to patients along with anti-tubercular treatment.
Patients with evidence of vitamin B6 deficiency may require doses upto 50mg/day.
it is mostly used to treat gout
In rare instances, treatment with oral pyridoxine (a B-complex vitamin) benefits patients whose sideroblastic anemia was present at birth. This treatment improves the condition of some patients but does not cure the anemia.
The treatment of tuberculosis is possible.
Antituberculosis medication of multidrug regime for 9 months. Four medicines for two months followed by two medicines for seven months. The duration and medicines differ from time to time from country to country depending on its National Tuberculosis Treatment Programme. The medicines used are Isoniazide, Rifampicin, Ethambutol, Pyrazinamide. Pyridoxine is always added along with Isoniazide.
XDR or extremely drug resistant tuberculosis is at a form of tuberculosis which does not respond to usual tb treatment.
Even after 2 months of treatment, there is a small chance that tuberculosis can be infectious, which is why a new sputum test must be taken.
Yes, pyridoxine hydrochloride is a chemical compound. It is the hydrochloride salt form of pyridoxine, which is a form of vitamin B6. It is commonly used in dietary supplements and medications to treat vitamin B6 deficiency.
yes but it is uncommon
They are a combination of antitubercular drugs used for the treatment of Tuberculosis. AKT-4 contains four medicines (Rifampicin + Isoniazid + Pyrazinamide + Ethambutol) all used in the treatment of TB.
It has a calming effect on the nervous system, and may alleviate insomnia by increasing serotonin levels in the brain. Because of the calming effects of pyridoxine, it has been tried as a possible adjunctive treatment for schizophrenia
Yes you can if you have finished your treatment
The most effective treatment for tuberculosis infection is a combination of antibiotics, typically including isoniazid, rifampin, ethambutol, and pyrazinamide. Treatment usually lasts for six to nine months to ensure complete eradication of the bacteria. It is important to follow the prescribed treatment regimen consistently to prevent the development of drug-resistant strains of tuberculosis.