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Mumps can lead to sterility in adult males primarily due to orchitis, an inflammation of the testicles that can occur after infection. This inflammation can damage the testicular tissue, affecting sperm production. In contrast, women and children are generally less impacted by mumps in terms of reproductive health, as females have a different reproductive anatomy and the ovaries are not typically affected by the virus in the same way. Additionally, children are often less likely to experience severe complications from mumps.

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