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Protamine is used with insulin to create a longer-acting formulation, often referred to as protamine insulin or NPH insulin. It acts by binding to insulin, which slows its absorption and prolongs its action in the body. This combination helps in managing blood sugar levels over an extended period, making it suitable for patients who require basal insulin support. The use of protamine allows for a more stable and sustained release of insulin, improving glycemic control.

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1mo ago

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Related Questions

How can the action of extracted insulin be prolonged?

Its action can be prolonged by using crystalline zinc insulin complexes, Lente preparations or protamine zinc insulin complexes. All of these complexes are in suspended form for subcutaneous administration.


How is protamine sulfate used for an antidote for heparin?

Protamine sulfate is an antidote for heparin. It is taken when heparin toxicity has been discovered in patients and removes the anticoagulant effects of the drug.protamine sulphate protamine sulphate


Are vit k and protamine sulfate the same?

No, vitamin K and protamine sulfate are not the same. Vitamin K is a fat-soluble vitamin that plays a key role in blood clotting, while protamine sulfate is a medication used to reverse the effects of heparin, an anticoagulant.


Is nph used on a sliding scale?

No, NPH (Neutral Protamine Hagedorn) insulin is a type of intermediate-acting insulin that typically has a more consistent effect over a longer period of time compared to short-acting insulins. It is usually given at a fixed dose rather than on a sliding scale based on blood glucose levels.


Which insulins are in suspensions?

Insulins that come in suspension form include NPH (Neutral Protamine Hagedorn) insulin and certain mixtures like 70/30, which contains 70% NPH and 30% regular insulin. These suspensions require gentle mixing before injection to ensure proper dosing, as the insulin particles can settle over time. Other insulin formulations, such as long-acting insulins like insulin glargine or insulin detemir, are typically not in suspension form.


What are intermediate-acting insulins?

NPH (neutral protamine Hagedorn) and Lente insulin are intermediate-acting, starting to work within one to three hours and lasting up to 18-26 hours.


What is anitdote to heparin?

Protamine Sulfate.


What drug reverses the effect of heparin?

Phytonadione (mephyton) is used to reverse the therapeutic effect of heparin


What does NPH stand for?

Neutral Protamine Hagedorn


What is anti dot to heparin?

Protamine Sulfate.


What is the brand name of protamine sulfate?

airwalk


What is another name for protamine sulfate?

Octaplex