Alcoholic ketoacidosis is the build up of ketones in the blood. Ketones are a type of acid that form when the body breaks down fat for energy.
The condition is an acute form of metabolic acidosis.
Alternative NamesKetoacidosis - alcoholic
Causes, incidence, and risk factorsAlcoholic ketoacidosis is caused by excessive alcohol use. It is most often seen in a malnourished person who drinks large amounts of alcohol every day.
SymptomsTreatment may involve fluids (salt and sugar solution) given through a vein. You may need to have your blood taken frequently.
People with this condition are admitted to the hospital, often to the intensive care unit (ICU).
Expectations (prognosis)Prompt medical attention improves the overall outlook.
ComplicationsThis can be a life-threatening disorder. Patients with alcoholic ketoacidosis often have or develop gastrointestinal bleeding, pancreatitis (inflammation of the pancreas), and pneumonia.
Calling your health care providerIf you or someone else has symptoms of alcoholic ketoacidosis, seek emergency medical help.
PreventionLimiting the amount of alcohol you drink may help prevent this condition.
ReferencesCho KC, Fukagawa M, Kurokawa K. Fluid and electrolyte disorders. In: McPhee SJ, Papadakis MA, eds. Current Medical Diagnosis and Treatment. 48th ed. New York, NY: McGraw-Hill; 2009:chap 21.
DuBose TD Jr. Acidosis and alkalosis. In: Fauci A , Kasper D, Longo DL, et al, eds. Harrison's Principals of Internal Medicine. 17th ed. New York, NY: McGraw Hill; 2008:chap 48.
Ketosis is the state of having elevated ketone bodies in the blood stream. Ketone bodies are formed by ketogenesis when liver glycogen stores are depleted. Ketone bodies are acidic, and prolonged exposure can overrun the compensatory mechanisms resulting in ketoacidosis ( pH under 7.35). Most commonly, ketoacidosis is diabetic ketoacidosis (DKA), resulting from increased fat metabolism due to a shortage of insulin. It is associated primarily with type I diabetes, and may result in a diabetic coma if left untreated. In alcoholic ketoacidosis, alcohol causes dehydration and blocks the first step of gluconeogenesis. The body is unable to synthesize enough glucose to meet its needs, thus creating an energy crisis resulting in fatty acid metabolism, and ketone body formation.
Alcohol can cause metabolic acidosis due to its influence on metabolism and disruption of the acid-base balance in the body. However, chronic alcohol use can also lead to conditions such as alcoholic ketoacidosis, which is a specific type of metabolic acidosis associated with excessive alcohol consumption.
alcoholic and non alcoholic
A measure of the bicarbonate level in the blood based on a venipuncture specimen. The serum carbon dioxide is one of the normally reported values in the electrolytes profile. Lower levels of carbon dioxide indicate an acidosis. The normal level is 20 to 29 mEq/L. Lower than normal levels can indicate diabetic ketoacidosis, lactic acidosis, alcoholic ketoacidosis, kidney disease, renal failure, diarrhoea, Addison's disease, ethylene glycol poisoning or methanol poisoning. Greater than normal levels can be seen with excessive vomiting, hyperaldosteronism and Cushing's syndrome.
Tea isn't alcoholic.
You say "I am an alcoholic."
He is not an alcoholic, but he does drink.
I am an Alcoholic.
alchoholic+ship=pirate
A correct prefix to add to "alcoholic" could be "non-," changing it to "non-alcoholic," which means without alcohol.
An alcoholic drink.
An alchie is a slang term for an alcoholic.