Collagen vascular disease

Answer 1

Definition

Collagen is a tough, glue-like protein that makes up 30% of body protein. It shapes the structure of tendons, bones, and connective tissues. Problems with the immune system can affect these structures. This is known as collagen vascular disease.

Collagen vascular diseases include:

• Dermatomyositis
• Polyarteritis nodosa
• Rheumatoid arthritis
• Scleroderma
• Systemic lupus erythematosus

Symptoms

Symptoms of collagen vascular disease may include:

• Anemia
• Fever
• Joint inflammation
• Weakness

Answer 2

Definition

Collagen vascular disease occurs when problems with the immune system affect collagen.

Collagen is a tough, fiber-like protein that makes up 30% of body protein. It contributes to the structure of tendons, bones, and connective tissues.

In a class of diseases known as autoimmune disorders, the body's immune system attacks its own tissues. Some of these diseases have similarities, including Arthritis and inflammation of arteries in the tissues that connect joints and other tissues. These diseases are known as collagen vascular diseases.

Collagen vascular diseases include:

• Ankylosing spondylitis
• Dermatomyositis
• Polyarteritis nodosa
• Psoriatic arthritis
• Rheumatoid arthritis
• Scleroderma
• Systemic lupus erythematosus

Symptoms

Symptoms of collagen vascular disease vary from disease to disease, but may include:

• Back pain
• Chest pain and shortness of breath
• Fatigue and weakness
• Fever
• Painful, swollen joints
• Rashes

Reviewed By

Review Date: 02/09/2011

Michael E. Makover, MD, professor and attending in Rheumatology at the New York University Medical Center, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.