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A test for platelet-associated antibodies shows whether you have antibodies that are directed against platelets in your blood.
How the test is performedBlood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The area is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.
Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.
In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.
How to prepare for the testNo special preparation is necessary for adults.
How the test will feelWhen the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.
Why the test is performedThis test may be ordered when you have a low platelet count (thrombocytopenia). It is used to detect antibodies against platelets.
Normal ValuesA negative test is normal.
Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
What abnormal results meanAbnormal results show that you have antiplatelet antibodies. These are proteins made by the body that attach to platelets and destroy them. This causes a low platelet count, which can lead to excessive bleeding.
Antiplatelet antibodies may appear in the blood for unknown reasons (idiopathic thrombocytopenic purpura), or as a side effect of certain drugs such as heparin. These drugs can sometimes cause the immune system to identify its own platelets as abnormal or foreign, and attack them.
What the risks areVeins and arteries vary in size from one patient to another, and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight but may include:
- Excessive bleeding
- Fainting or feeling light-headed
- Hematoma (blood accumulating under the skin)
- Infection (a slight risk any time the skin is broken)
Current tests cannot tell for sure whether a low platelet count (thrombocytopenia) is caused by immune problems. Therefore, your doctor will make a diagnosis based on other tests and examinations.
This test is often performed because you have a bleeding problem. Bleeding may be more of a risk for you than for people who do not have bleeding problems.
ReferencesMcMillan R. Hemorrhagic disorders: Abnormalities of platelet and vascular function. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 179.
What else can I help you with?
What test a screening test to evaluate platelet function and to monitor changes in the blood associated with chemotherapy and radiation therapy?
Platelet Count
What does pit mean on a blood test?
"PIT" on a blood test typically refers to "Platelet Immune Test," which is used to assess the presence of antibodies that may be causing low platelet levels or platelet dysfunction. It helps diagnose conditions such as immune thrombocytopenia.
What medical condition is associated with platelets?
Disorders of the bone marrow and systemic conditions can cause an elevated platelet count. An elevated platelet count is known as thrombocytosis. A high platelet count can signal a more serious blood problem known as a myeloproliferative disorder
What is a normal PDW hematology result?
A normal platelet distribution width (PDW) result typically ranges from 9.0% to 14.0%. PDW measures the variability in platelet size, and values within this range suggest a stable platelet population. Elevated PDW levels may indicate conditions such as platelet activation or disorders, while low levels can suggest a uniform platelet size, often associated with certain bone marrow conditions. It's essential to interpret PDW results in conjunction with other hematological parameters for a comprehensive assessment.
Do platelet cells decrease with age?
Yes, platelet counts can decrease with age, but the extent and significance of this decline can vary among individuals. Older adults may experience changes in platelet production and function, which can contribute to age-related health issues. However, it’s important to note that not all elderly individuals will have lower platelet counts, and some may maintain normal levels. Regular monitoring and assessment by healthcare professionals can help manage any potential risks associated with aging and platelet levels.
Low platelet count?
platelet count
What is the Platelet Count Test?
What is the Platelet Count Test?
How many platelet transfusions can a leukemia patient have?
As many as necessary to prevent bleeding associated with thrombocytopenia. In patients refractory to random donor platelet transfusions, platelet crossmatching may identify units providing better platelet count increases. If crossmatching is not effective, HLA matching of platelets may be necessary.
What does high mpv and pdw mean?
High MPV (Mean Platelet Volume) indicates that platelets are larger than average, which may suggest increased platelet production or activation, often associated with conditions like inflammation or certain blood disorders. High PDW (Platelet Distribution Width) reflects greater variability in platelet size, potentially indicating diverse platelet populations or an underlying disorder. Together, elevated MPV and PDW can signal issues like thrombocytopenia, myeloproliferative disorders, or other inflammatory conditions, warranting further investigation by a healthcare professional.
Does a hyperactive spleen cause platelet deficiency?
No, a hyperactive spleen does not directly cause platelet deficiency. Platelet deficiency is typically due to decreased platelet production in the bone marrow or increased platelet destruction in the body, such as in immune thrombocytopenia. However, a splenic disorder or enlargement can sometimes lead to increased platelet destruction and contribute to low platelet levels.
How do you increase platelet count?
Platelet counts can be increased through diet. There are several foods that can increase platelet counts, some of these foods include kale, spinach, and tofu.
How much will be the platelet count after tranfuse one unit of platelet rich plasma?
1 unit prp increases platelet count by 10,000.
