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What does low therapeutic index mean?
Drugs with a low therapeutic index have a narrow margin of safety.
What is the opisthion index of homo sapiens?
The opisthion index measures the relative position of the opisthion (the midpoint of the posterior margin of the foramen magnum) in relation to the basion (the midpoint of the anterior margin of the foramen magnum). In Homo sapiens, the opisthion index typically falls between 0.52 and 0.58.
The index plus the margin chosen by lender results in what rate?
The index plus the margin chosen by the lender results in the fully indexed interest rate for an adjustable-rate mortgage (ARM). The index is a benchmark interest rate that reflects market conditions, while the margin is a fixed percentage added by the lender to determine the borrower's interest rate. Together, they establish the rate at which the borrower will be charged, which can fluctuate based on changes in the index. This combined rate affects the borrower's monthly payments over the life of the loan.
IN an adjustable rate mortgage is a margin added to give a full interest rate?
Most ARM loans are based on a mortgage index. Common indexes are LIBOR, CMT, T-Bill and COFI. That index is added to the margin to create the fully indexed interest rate.
What is margin money on letter of credit?
Margin money on a letter of credit is the part of the interest rate that is over the adjustment-index rate. It is the part that is retained as profit by the one doing the lending.
Who sets the margin for an adjustable rate mortgage?
The issuing bank sets the margin for an adjustable rate mortgage (ARM), which is typically an additive offset from a well-known index like the prime rate or LIBOR.
Is therapeutic index a useful measure of safety?
It is for certain drugs such as Digoxin as they have such a narrow therapeutic index. For drugs with a wide range of therapeutic index, the best measure of safety is the maximum daily dose, its effect on the patient and what other drugs it interacts with. Ask your pharmacist for specific safety questions on your specific drugs.
The dose of a drug which kills 50 animals was 60mgkg the dose of a drug which cured 50 animals was20mgkg calculate the therapeutic index of the drug?
The therapeutic index of a drug is determined by dividing the lethal dose (LD50) by the effective dose (ED50). In this case: Therapeutic index = LD50/ED50 = 60mg/kg / 20mg/kg = 3. This means that the drug has a therapeutic index of 3, indicating a relatively safe drug with a wide margin of safety.
How are adjustable rate mortgages calculated?
Adjustable rate mortgages are calculated based on a specific index, such as the prime rate or LIBOR, plus a margin set by the lender. The interest rate can change periodically, usually annually, based on fluctuations in the index.
What do index values in mortgages mean?
Indexes only apply to adjustable rate mortgages (ARM). In order to determine your new interest rate on an ARM after the initial fixed rate period, the new rate is determined by adding your "base margin" (your ground zero of the loan normally 2.75%) to the current index your loan is attached to. There are several indexes out there - the most popular being the LIBOR index or US Treasury index. Your margin percentage is added to the index and rounded to the nearest 1/8 of one per cent which determines your new loan interest rate. So indexes are the moving percentages that are tied to Wall Street and the world markets that influence interest rates.
On a topographic map where would you locate the contour interval in the margin?
It would be the difference between the two darker lines, or index lines, and then divide the space in between with your difference.
How is your ARM rate determined?
The Adjustable-rate mortgage(ARM) rate is determined by interest rate, adjustment period, index rate, the margin,discount, prepayment, and many other factors.
