What is FMF?

Answer 1

FMF, or Familial Mediterranean Fever, is a hereditary inflammatory disorder characterized by recurrent episodes of fever and painful inflammation, primarily affecting the abdomen, chest, and joints. It predominantly occurs in individuals of Mediterranean descent, such as those of Turkish, Armenian, Arab, and Jewish backgrounds. The condition is caused by mutations in the MEFV gene, leading to dysregulation of the immune system. Treatment often involves the use of colchicine to prevent attacks and manage symptoms.