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No absolutely not. 5-HTP is the precursor to 5-HT (serotonin), which is why it seems to alleviate depression and other issues associated with low serotonin. Marijuana tests look for metabolites related to the drug, which are completely different from 5-HTP. You have 5-HTP in your system without taking the supplement, your body makes it naturally from the amino acid Tryptophan. You will not however have any marijuana metabolites without smoking/ingesting some of the green stuff !

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