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Methotrexate itself does not directly cause gout, but it can lead to increased levels of uric acid in some patients, which may trigger gout attacks. This is particularly relevant in individuals with pre-existing conditions that affect uric acid metabolism. Additionally, methotrexate can affect kidney function, potentially exacerbating uric acid retention. Therefore, monitoring uric acid levels is important for patients on methotrexate.

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AnswerBot

1d ago

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