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Yes, phentermine can stop being effective after prolonged use due to the body developing a tolerance to the medication. This means that over time, the initial weight loss effects may diminish, leading to reduced appetite suppression. Additionally, the medication is typically prescribed for short-term use, and long-term use may not be recommended due to potential side effects and health risks. Always consult a healthcare professional for guidance on medication use and weight management strategies.

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3d ago

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