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Benzo and Thienodiazepines are a wide class of sedative hypnotic GABAergic positive allosteric modulators acting at the Gamma Amino Butyric Acid alpha subunit site, being eithers agonists, mixed agonist antagonists, and antagonists at this site. It's hard to classify unless one specific drug is named, for example, Flunitrazepam is known to be much more effective than alprazolam when smoked, snorted, used rectally, or orally, by mechanisms of both potency and bio-availability.

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