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Whenever you have a question about drug interactions, even with grapefruit juice (no kidding, there are some drugs that react to grapefruit) CALL YOUR PHARMACY! Never risk it. Ever. Codeine is made from opium (like morphine and heroin) and is a depressant, so is alcohol. They are more than the sum of their parts. Think of it this way if you are drugged 3 out of 10 on codeine and you consume enough alcohol to be drunk a 3 out of 10 you won't end up intoxicated a 6 (3 + 3). You will be a 9 (3 x 3). Do not use alcohol with pain killers, including aspirin. Do not use alcohol with anti-depressants. Read your pill labels. And, if you do consume alcohol (or anything) with a drug and feel really unwell, if at all possible, take the pills with you to the hospital. They need to know *exactly* what is in your blood. (A helpful aside, in a lot of states only minors can be prosecuted for possession based on a blood test. Adults can have anything in their blood as long as it isn't on their person and be legally safe. It's always better to tell the doctors the truth.) Be safe! A couple of drinks just isn't worth it. There will be beer another day.

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