Can you take Ativan and Ambien together?

Answer 1

Disclaimer: I am not a pharmacist or medical doctor. Please check with one of these before taking my word for this, just to be safe. This is based on my personal experience and subsequent discussions with my doctor.

Sure, you can take them together, as long as you are taking no more than the prescribed doses of each. You probably will not want to, though. Ativan and Ambien bind competitively to the same receptors, with Ativan having a higher affinity.

In other words, the Ativan will overpower the Ambien. You will get little to no effect from the Ambien. You might as well be flushing the Ambien down the toilet (though please don't do that, take unwanted drugs to your local pharmacy for safe disposal).

Ativan is digested relatively quickly, so if you plan to take Ambien for sleep, you could probably get away with a noon or even afternoon dose of Ativan that day, if you take daytime doses, but you may have to experiment a bit to figure out what works for you.

Answer 2

Not unless explicitly directed to by a physician. Mixing these two can lead to some terrible unintended side-effects.