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If you have Lorazepam and Oxycontin you won't even need Lexapro. Lexapro is a drug that selectivly inhibits the reuptake of seritonin in the prensynaptic neuron, thus flooding the synapse with seritonin premoting the effects of seritonin in the postsynaptic neuron. It is prescribed often for anxiety and depression, but can also cause weight gain, an increase in anxiety and/or depression for the first two weeks of use, and drowsiness. Where as Lorazepam, a benzodiazapine, effects GABA receptors in a way much more noticebly decreasing anxiety; also Oxycontin is an opiate that increases dopamine release, producing a euphoric and analgesic effect. So it would be possible to take these drugs together to excite a numerous amount of chemicals in your brain in niether an agonistic or antagonistic way, therefore reducing the risk of overdose; however Lexapro on top of these two drugs would not have much of a noticible effect and in fact could make you feel slightly nauseated. I also would not suggest taking Lexapro unless you have been on it for a while.

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15y ago

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