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You can overly suppress your system causing death. Never combine these medications EVER I've been taking xanax and cymbalta together for 2 years now with no adverse reactions so I'm curious about this response?? Cymbalta does not "supress your system", it is an SSNRI and has no effect on the GABA receptors in the brain which Xanax works through.

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16y ago

What else can I help you with?