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The combination of antidepressants and certain drugs can have interesting effects on your brain in a physical sense, not just mental ;)

The first thing that comes to mind is Serotonin Syndrome. This is a result of combining drugs that stimulate or mimic serotonin activity (antidepressants) and other drugs that induce a release of serotonin (DXM, LSD, amphetamines, psilocybin, DMT... this is a long list). This can be fatal.

For those who aren't familiar with the terms I used, I'll break it down. Antidepressants give you a happy chemical in your brain. Taking certain drugs will give you too much of this happy chemical in combination with antidepressants.

If you don't know, don't risk it. It could be a fatal mistake! Props to you for asking. Drugs are risky business and it's ALWAYS best to be educated before you take any of them. You have one body, take care of it.

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14y ago

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