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I am on 20mg/day Suboxone and have been prescribed 8mg Zanaflex/day and haven't had any sort of bad reaction to the combo. I've taken my Zanaflex at the same time as the Sub and still all has been fine. Just a word of warning, Tizanidine (Zanaflex) is really harsh on the liver and you should be careful if taking it long term.

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11y ago

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