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YES, it is safe to take Mucinex while taking Methadone. I contacted a pharmacist to confirm that it is safe, because I needed to know the same thing. They told me it is safe but they wouldn't take them directly together. She said to wait like an hour or so between each medicine. Then she said that is a good rule of thumb for any medications that you are taking. So yes, you can take them together just wait an hour in between.

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14y ago

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