Can you take pseudoephedrine with Vicodin?

Answer 1

I'm going to assume the question is about recreational drug use. If you're just taking them as directed you'll be fine.

This combination is similar to a speedball (heroin + cocaine), but weaker. Speedballs are notorious for killing people - the cocaine wears off before the heroin and breathing stops, etc. That said, it would be really hard to take enough vicodin to die from an overdose. You'd probably die first from liver damage from the acetaminophen in them.

The bigger problem is the pseudoephedrine. Pseudoephedrine has a much stronger effect on the body than the brain, so if you're taking enough to get high, it's really hard on your body: you're liable to have a heart attack or stroke. Ephedrine (Bronkaid tablets) is better - at the dose needed to get high it has less effect on the body. Amphetamine is even better (but more addictive).

Aside from physical dangers, this sort of combination is about the most addictive thing you can imagine. I know from experience. Please be careful.