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This is from the manufacturers of Tramadol.

Seizures (convulsions) have occurred in some people taking tramadol. You may be more likely to have a seizure while taking tramadol if you have a history of seizures or head injury, a metabolic disorder, or if you are taking certain medicines such as antidepressants, muscle relaxers, or medicine for nausea and vomiting.

Seroquel falls more into the category of an antipsychotic but on its PIL (patient information leaflet) it states that it helps with depression so I would consult either a G.P. or pharmacist first.

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15y ago

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