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Yes, Suboxone and Benadryl can be taken together since there is no adverse interaction between the two drugs. Quite often antihistamines like Benadryl are taken with opiates (Suboxone contains an opiate and an opiate antagonist) to slightly heighten the effect of the opiate, but antihistamines don't dangerously heighten the effect, if they even heighten it at all. This can be verified on Medscape by using that website's drug interaction checker. I entered Suboxone and Benedryl and no interactions were found.

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14y ago

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